Key result
Obesity linked to ~5-fold higher peri-anaesthetic mortality during non-cardiac surgery in resource-limited settings.
Why the study?
Anaesthesia in obese patients is characterised by complications due to comorbidities and physiological changes, prompting investigation of peri-anaesthetic complications in obese versus non-obese patients under resource-limited conditions.
Does obesity increase peri-anaesthetic complications and mortality in patients undergoing non-cardiac surgery in a limited-resource setting?
Cohort (n=2,718)
No
Does obesity increase peri-anaesthetic complications and mortality in patients undergoing non-cardiac surgery in a limited-resource setting?
In a limited-resource setting, obesity is a significant risk factor for peri-anaesthetic morbidity and mortality during non-cardiac surgery.
Obesity may warrant heightened peri-operative vigilance in resource-limited settings; leaves open causal confirmation and mitigation strategies.
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Mombeleke et al. (2025) conducted a cohort in Peri-anaesthetic complications in non-cardiac surgery (n=2,718). Obesity vs. Non-obese was evaluated on Mortality (ORa 5.1, 95% CI 2.21 - 7.5, p=<0.04). Obesity significantly increased peri-anaesthetic mortality compared to non-obese patients (2.72% vs 0.8%, ORa 5.1) undergoing non-cardiac surgery in a resource-limited setting.
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