Neurosarcoidosis, Could It Be? - Case Report

This is the authors' abstract. We don't add key points for this paper.

While the clinical presentation of systemic sarcoidosis is well established, identification of isolated neurologic sarcoidosis remains a diagnostic challenge. Isolated neurologic sarcoidosis, or neurosarcoidosis, presents in a manner that is often indistinguishable from other neurological diseases. Common clinical features include headache, encephalopathy, gait disturbance, seizure, behavioral abnormalities, sleep difficulties, loss of appetite, cranial mononeuropathy (including visual, auditory, and vestibular dysfunction), myelopathy, radiculopathy, myopathy, and peripheral neuropathy. While probable diagnosis requires only evidence of inflammation on cerebrospinal fluid studies or magnetic resonance imaging, tissue biopsy with pathologic findings of noncaseating granulomas is required for definitive diagnosis. We present the case of a 54-year-old male with headache, episodic confusion, and gait disturbance attributed to probable neurologic sarcoidosis.