PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
June 25, 2025Open Access

β-bursting as a sensitive neural marker of inhibitory control in healthy older adults: a linear mixed-effects modelling and threshold-free cluster approach

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Inhibitory control declines with age, but the underlying neural dynamics remain poorly understood, and transient beta-bursts supporting inhibition are often masked by conventional trial-averaged beta-power analyses.

Comparison

Beta-bursting dynamics during response inhibition vs response initiation

Design

Experimental neurophysiological study

Key result

Trial-by-trial analysis of β-bursting during response inhibition revealed distinct spatiotemporal patterns and a functional link to muscle-level suppression absent in averaged β-power data.

Authors

AWAliya C. M. WardenDCDamian CruseCMCraig McAllister

Discussion

Loading...

Member takes

Overview

Trial-level β-burst analysis may sensitively index motor inhibition; leaves open validation in clinical populations.

Study Design

Type

Observational (n=20)

Structured PICO

P
Population
20 healthy older adults
I
Intervention
Bimanual anticipatory response inhibition task with electroencephalography (EEG) and electromyography (EMG) recording, analyzed using linear mixed-effects modelling (LMM) with threshold-free cluster enhancement (TFCE)
O
Outcome
Spatiotemporal β-bursting patterns (rate/duration) and averaged β-power during response inhibition and initiationsurrogate

β-bursting, analyzed via LMM-TFCE, provides a sensitive, trial-level marker of inhibitory control and cortical suppression of motor output in healthy older adults.

Cite This Study

Warden et al. (2025) conducted an observational in Healthy older adults (n=20). Bimanual anticipatory response inhibition task with EEG and EMG was evaluated on Spatiotemporal β-bursting patterns and muscle bursting dynamics. Trial-by-trial analysis of β-bursting during response inhibition revealed distinct spatiotemporal patterns and a functional link to muscle-level suppression absent in averaged β-power data.

synapsesocial.com/papers/6a11d9fe0aad52b339b4ca8dhttps://doi.org/10.1101/2025.06.21.660835
View Full Paper
Ask AI
Bookmark
Share