Transdiagnostic psychopathology factors and sexual minority mental health: Evidence of disparities and associations with minority stressors.

= 34,653). Twelve-month diagnoses of 13 common mood, anxiety, substance use, and personality disorders were modeled, and multi-group analysis indicated a sexual orientation-invariant trans-diagnostic latent structure. Significant disparities at the latent trans-diagnostic factor level were observed; these factor-level disparities are manifested as observed mental disorder disparities. Gender differences typically seen in trans-diagnostic research were not present between sexual minority women and men. Trans-diagnostic internalizing and externalizing factors were then used as outcomes in a minority stress framework and were positively predicted by lifetime history of sexual orientation-related minority stressors (i.e., discrimination and victimization). Implications for using trans-diagnostic approaches to frame intervention efforts, supplement disorder-by-disorder disparities methodologies, and synthesize piecemeal disparities literatures are discussed.