Obesity surgery significantly reduced obesity-related co-morbidities over 5 years, halving diabetes-related hyperglycemia, with a morbidity of 3.1% and in-hospital mortality of 0.07%.
Observational
Yes
Does obesity surgery improve obesity-related co-morbidities in a real-world UK population?
Real-world data from the UK National Bariatric Surgery Registry demonstrates that obesity surgery safely and substantially improves multiple obesity-related comorbidities, including diabetes and hypertension, over 5 years.
BACKGROUND: The National Bariatric Surgery Registry (NBSR) is the largest bespoke database in the field in the United Kingdom. OBJECTIVES: Our aim was to analyze the NBSR to determine whether the effects of obesity surgery on associated co-morbidities observed in small randomized controlled clinical trials could be replicated in a "real life" setting within U.K. healthcare. SETTING: United Kingdom. METHODS: All NBSR entries for operations between 2000 and 2015 with associated demographic and co-morbidity data were analyzed retrospectively. RESULTS: . Over 5 years of follow-up, statistically significant reductions in the prevalence of type 2 diabetes, hypertension, dyslipidemia, sleep apnea, asthma, functional impairment, arthritis, and gastroesophageal reflux disease were observed. The "remission" of these co-morbidities was evident 1 year postoperatively and reached a plateau 2 to 5 years after surgery. Obesity surgery was particularly effective on functional impairment and diabetes, almost doubling the proportion of patients able to climb 3 flights of stairs and halving the proportion of patients with diabetes related hyperglycemia compared with preoperatively. Surgery was safe with a morbidity of 3.1% and in-hospital mortality of .07% and a reduced median inpatient stay of 2 days, despite an increasingly sick patient population. CONCLUSIONS: Obesity surgery in the U.K. results not only in weight loss, but also in substantial improvements in obesity-related co-morbidities. Appropriate support and funding will help improve the quality of the NBSR data set even further, thus enabling its use to inform healthcare policy.
Miras et al. (Wed,) conducted a observational in Obesity. Obesity surgery vs. Preoperative baseline was evaluated on Prevalence of obesity-related co-morbidities. Obesity surgery significantly reduced obesity-related co-morbidities over 5 years, halving diabetes-related hyperglycemia, with a morbidity of 3.1% and in-hospital mortality of 0.07%.