Key result
The modified cardiovascular SOFA score outperformed the existing score for predicting in-ICU mortality (AUROC 0.801 vs 0.718; difference = 0.083; p < 0.001).
Why the study?
Does a modified cardiovascular component of the SOFA score improve prediction of mortality in adult ICU patients compared to the existing score?
Cohort (n=16,386)
No
Does a modified cardiovascular component of the SOFA score improve prediction of mortality in adult ICU patients compared to the existing score?
Effect estimate: Difference 0.083
Absolute Event Rate: 0.801% vs 0.718%
p-value: p=<0.001
A modified cardiovascular SOFA score incorporating current vasoactive agents, shock index, and serum lactate significantly improves mortality prediction in ICU patients compared to the traditional score.
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Yadav et al. (2015) conducted a cohort in ICU admissions (n=16,386). Modified cardiovascular component of the Sequential Organ Failure Assessment score vs. Existing cardiovascular component of the Sequential Organ Failure Assessment score was evaluated on In-ICU mortality prediction (AUROC) (Difference 0.083, p=<0.001). The modified cardiovascular SOFA score outperformed the existing score for predicting in-ICU mortality (AUROC 0.801 vs 0.718; difference = 0.083; p < 0.001).
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