Key result
Managing acute stroke in AF requires individualized risk-benefit assessment for acute and long-term preventive strategies.
Why the study?
AF-related strokes carry high disability and mortality, making acute management and preventive strategies challenging due to the need to balance ischemic stroke reduction against systemic bleeding risks.
This review outlines the complex risk-benefit considerations in the acute and long-term management of stroke in patients with atrial fibrillation.
Supports individualized AF-stroke decisions; leaves open need for targeted trials on acute and preventive strategies.
Atrial fibrillation (AF) is an important risk factor for ischemic stroke (IS). Oral anticoagulation (OAC) significantly reduces the risk of IS in AF but also increases the risk of systemic bleeding, including intracerebral hemorrhage (ICH). AF-related strokes are associated with greater disability and mortality compared to non-AF strokes. The management of patients with AF-related strokes is challenging, and it involves weighing individual risks and benefits in the acute treatment and preventive strategies of these patients. This review summarizes the current knowledge of the acute management of ischemic and hemorrhagic stroke in patients with AF, and the prognosis and potential implications for management both in the acute and long-term setting.
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Hindsholm et al. (2023) conducted a review in Acute stroke in atrial fibrillation. Acute management of stroke in patients with atrial fibrillation requires carefully weighing individual risks and benefits for both acute treatment and long-term preventive strategies.
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