Key result
Inclusion of oral anticoagulation therapy significantly correlated with increasing duration of pacemaker-detected atrial fibrillation episodes (r = 0.502, p = 0.003).
Why the study?
Does oral anticoagulation therapy guided by the duration of pacemaker-detected atrial fibrillation prevent thrombo-embolic complications in patients with permanent pacemakers?
Observational (n=104)
Does oral anticoagulation therapy guided by the duration of pacemaker-detected atrial fibrillation prevent thrombo-embolic complications in patients with permanent pacemakers?
No thromboembolic events occurred despite OAC correlation with longer AF episodes; leaves open whether duration-guided anticoagulation prevents complications.
INTRODUCTION: In patients with an implanted pacemaker, asymptomatic atrial fibrillation (AF) is associated with an increased risk of thrombo-embolic complications. There is still no consensus which duration of episodes of atrial fibrillation should be taken as an indicator for inclusion of oral anticoagulation therapy (OAC). MATERIAL AND METHODS: A total of 104 patients who had no AF episodes in the past and have an indication for permanent pacing were included in the study. RESULTS: During an average follow-up of 18 months, 33 of the patients developed episodes of AF. Inclusion of OAC was performed in 17 patients, in whom AF was recorded, although in all patients CHA2DS2-VASc score was ≥ 1. The inclusion of OAC showed a statistically significant correlation with increasing duration of episodes of AF (r = 0.502, p = 0.003). During the follow-up period none of the patients developed thrombo-embolic complication. CONCLUSION: Considering that our group of patients had no thrombo-embolic events, we could conclude that dividing the AF episodes in less than 1% in 24 hours and longer than 1% within 24 hours could be an indicator for decision-making to include OAK if the CHA2DS2-VASc score is ≥ 1.
No takes yet. Share an insight, caveat, or question.
Poposka et al. (2016) conducted an observational in Pacemaker-detected atrial fibrillation (n=104). Oral anticoagulation therapy (OAC) was evaluated on Correlation between inclusion of OAC and duration of AF episodes (r = 0.502, p=0.003). Inclusion of oral anticoagulation therapy significantly correlated with increasing duration of pacemaker-detected atrial fibrillation episodes (r = 0.502, p = 0.003).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: