Key result
EEG and HRV parameters showed strong canonical correlations with blood leukocyte levels (r=0.92, p<10-5) in men with chronic pyelonephritis and cholecystitis in remission.
Cross-Sectional (n=23)
Effect estimate: r=0.92
p-value: p=<10-5
Parameters of white blood cell count are significantly correlated with electrical activity of the central and autonomic nervous systems, suggesting neuro-immune modulation.
Correlations may indicate neuro-immune modulation in remission; hypothesis-generating and requires prospective validation before any clinical use.
We aim to analyze in bounds KJ Tracey's immunological homunculus conception the relationships between parameters of electroencephalogram (EEG) and heart rate variability (HRV), on the one hand, and the parameters of bhite blood cell count, on the other hand. METHODS: In basal conditions in 23 men, patients with chronic pyelonephritis and cholecystitis in remission, recorded EEG ("NeuroCom Standard", KhAI Medica, Ukraine) and HRV ("Cardiolab+VSR", KhAI Medica, Ukraine). In portion of blood counted up white blood cell count. RESULTS: Revealed that canonical correlation between constellation EEG and HRV parameters form with blood level of leukocytes 0.92 (p<10-5), with relative content in white blood cell count stubnuclear neutrophiles 0.93 (p<10-5), segmentonucleary neutrophiles 0.89 (p<10-3), eosinophiles 0.87 (p=0.003), lymphocytes 0.77 (p<10-3) and with monocytes 0.75 (p=0.003). CONCLUSION: Parameters of white blood cell count significantly modulated by electrical activity some structures of central and autonomic nervous systems.
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Kul’chyns’kyi et al. (2017) conducted a cross-sectional in Chronic pyelonephritis and cholecystitis in remission (n=23). EEG and HRV parameters showed strong canonical correlations with blood leukocyte levels (r=0.92, p<10-5) in men with chronic pyelonephritis and cholecystitis in remission.
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