Key result
Outpatient cardiac rehab linked to ~27% lower frailty prevalence in cardiovascular patients over 80.
Why the study?
Older cardiovascular disease patients often have comorbidities like frailty, sarcopenia, and cognitive decline that reduce quality of life, prompting evaluation of outpatient cardiac rehabilitation in this population.
Does comprehensive outpatient cardiac rehabilitation improve frailty, physical function, quality of life, and exercise tolerance in patients aged ≥80 years with cardiovascular disease?
Observational (n=49)
No
Does comprehensive outpatient cardiac rehabilitation improve frailty, physical function, quality of life, and exercise tolerance in patients aged ≥80 years with cardiovascular disease?
Absolute Event Rate: 67.3% vs 91.8%
p-value: p=0.0015
Comprehensive outpatient cardiac rehabilitation safely and effectively improves physical frailty, exercise capacity, and quality of life in octogenarian patients with cardiovascular diseases.
May support outpatient cardiac rehabilitation to reduce frailty in octogenarians; hypothesis-generating pending randomized confirmation.
Background: Japan had the highest proportion of the elderly in the world, with one in 10 individuals aged ≥80 years. Consequently, the number of patients with cardiovascular diseases is increasing. Older patients often have comorbidities such as frailty, sarcopenia, and cognitive decline that leads to a decreased quality of life (QOL). We analyzed the effects of outpatient cardiac rehabilitation (OCR) in elderly patients with cardiovascular disease. Methods: The comprehensive OCR had been provided by a multidisciplinary team. We analyzed data from 49 patients with cardiovascular diseases, aged ≥80 years, who received cardiopulmonary exercise (CPX) tests based OCR. Frailty, physical function, QOL, exercise tolerance, and vascular endothelial function were assessed before and after OCR. Results: : 14.1 ± 4.0 vs. 15.4 ± 3.9 mL/min/kg; P = 0.0017), and vascular endothelial function (Ln-RHI: 0.48 ± 0.39 vs. 0.57 ± 0.3; P = 0.027) significantly improved after OCR. Conclusions: The comprehensive OCR with CPX-based exercise therapy and the multidisciplinary approach significantly improved frailty, the QOL, physical function, exercise tolerance, and vascular endothelial function in patients with cardiovascular diseases aged ≥80 years.
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Someya et al. (2025) conducted an observational in Cardiovascular diseases (n=49). Outpatient cardiac rehabilitation (OCR) vs. Baseline (pre-intervention) was evaluated on Frailty and pre-frailty prevalence (p=0.0015). Comprehensive outpatient cardiac rehabilitation significantly reduced the proportion of frailty and pre-frailty from 91.8% to 67.3% in patients aged ≥80 years with cardiovascular diseases.
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