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February 1, 1995The FASEB Journal

Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women

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Population

Obese women

Design

Cross-sectional

Authors

JSJean‐Aimé SimoneauSCSheri R. ColbergFTF. Leland Thaete

Discussion

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Overview

CT muscle attenuation may flag insulin-resistant muscle in obesity; hypothesis-generating for muscle metabolism as intervention target.

Structured PICO

P
Population
Obese women
O
Outcome
Relationship between skeletal muscle insulin sensitivity, mid-thigh muscle composition, and the metabolic profile of musclesurrogate

In obese women, skeletal muscle insulin resistance is associated with reduced oxidative capacity, increased glycolytic capacity, and increased fat storage within the muscle.

Cite This Study

Simoneau et al. (1995) studied this question.

synapsesocial.com/papers/6a1228061d9aa3bb4e342794https://doi.org/10.1096/fasebj.9.2.7781930
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