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The integration of artificial intelligence (AI) tools in the workflow of scholarly writing, including scientific and medical writing, offers transformative advantages while raising critical ethical and practical concerns. Among the pros, AI substantially enhances efficiency by automating several time-consuming tasks such as literature review, data synthesis and text editing. In particular, tools such as ChatGPT, Grammarly, and SciSpace Copilot remarkably empower researchers when they draft, refine, and format manuscripts, increasing precision and speed. In addition, AI tools may foster inclusivity by assisting non-native English speakers with seamless translations and also enabling interdisciplinary collaboration, thereby hopefully democratizing access and boosting scientific communication and cooperation. However, the rapid adoption of novel AI tools brings significant challenges. First, there is a distinct risk of perpetuating biases in training datasets, and other key issues include ambiguity in authorship accountability and the potential erosion of critical thinking skills. In addition, AI tools could be purposefully misused to generate mock datasets and fraudulent papers (e.g. by paper mills), and this clearly poses a threat to academic integrity. This challenge is all too pressing given that traditional plagiarism detection tools often fall short against sophisticated AI-generated content. We hereby explore the pros and cons of AI on medical writing, poignantly leveraging Sergio Leone’s The Good, The Bad, and The Ugly movie as a metaphor. By providing general concepts as well as focusing on several key AI tools, we are hopeful this overview may prove useful to anyone wishing to conscientiously adopt AI tools for scientific writing. In addition, we make a compelling case for transparent guidelines, robust and freely available detection mechanisms, and ongoing critical oversight to ensure AI will be able to serve as a catalyst for innovation and dissemination without compromising the credibility of scholarly endeavors.
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Biondi‐Zoccai et al. (2025) studied this question.
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