Key result
Incident cognitive impairment over a 10-year period increased the odds of impaired instrumental activities of daily living by 59% (OR 1.59; 95% CI 1.36-1.85).
Why the study?
The study examined the relationship between cognitive change and instrumental activities of daily living in a large, national, population-based sample.
Does longitudinal cognitive change predict impaired instrumental activities of daily living (IADL) in a general population?
Observational
Yes
Does longitudinal cognitive change predict impaired instrumental activities of daily living (IADL) in a general population?
Longitudinal cognitive decline over 10 years significantly predicts self-reported impairment in instrumental activities of daily living, particularly in managing finances and driving.
Answers are grounded in this paper and cite their sources.
Cognitive decline was associated with IADL impairment; hypothesis-generating for screening and prevention trials in aging populations.
This study examined the relationship between cognitive change and instrumental activities of daily living (IADL) in a large, national, population-based sample. Cognitive change was assessed via verbal fluency, word list learning (WLL), and word list delayed recall (WLD). Incident cognitive impairment was defined by change in Six-Item Screener (SIS) status over a period of 10 years. Impaired IADL was defined as self-reported difficulty or needing assistance performing any IADL at Year 10. A one-word decrease in WLL over a 10-year span increased the odds of impaired IADL by 16% (95% CI 1.08-1.24) and incident cognitive impairment increased the odds of impaired IADL by 59% (95% CI 1.36-1.85) when adjusting for demographic factors, health-related behaviors, vascular risk factors and disease, and depressive symptoms. Cognitive change most strongly predicted impairment in managing finances (OR 2.47, 95% CI 2.04-3.00) and driving (OR 2.06, 95% CI 1.73-2.44).
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Passler et al. (2019) conducted an observational in Cognitive impairment and impaired instrumental activities of daily living. Incident cognitive impairment vs. No incident cognitive impairment was evaluated on Impaired instrumental activities of daily living (IADL) at Year 10 (OR 1.59, 95% CI 1.36-1.85). Incident cognitive impairment over a 10-year period increased the odds of impaired instrumental activities of daily living by 59% (OR 1.59; 95% CI 1.36-1.85).
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