Key result
Radiofrequency ablation of the atrioventricular nodal slow pathway for AVNRT significantly reduced the effective refractory period of the fast pathway from 350 ms to 290 ms.
Why the study?
The study was conducted to determine potential changes in the conducting properties of the fast pathway after radiofrequency modification of the slow pathway for AVNRT that lead to failure of tachycardia induction.
Does radiofrequency modification of the slow pathway for AVNRT change the conducting properties of the fast pathway?
Population
171 patients with inducible typical AVNRT and dual AV nodal physiology
Comparison
Pre- vs post-slow pathway radiofrequency modification
Design
Single-centre observational study
Authors
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May explain post-ablation non-inducibility in AVNRT; hypothesis-generating, needs confirmation in prospective studies.
Observational (n=171)
No
Does radiofrequency modification of the slow pathway for AVNRT change the conducting properties of the fast pathway?
Absolute Event Rate: 290% vs 350%
p-value: p=0.0001
Ablation of the AV nodal slow pathway for AVNRT significantly shortens the effective refractory period of the fast pathway, which may contribute to the non-inducibility of the tachycardia.
Khan et al. (2019) conducted an observational in Atrioventricular nodal re-entrant tachycardia (AVNRT) (n=171). Radiofrequency ablation of the slow pathway vs. Baseline (pre-ablation) was evaluated on Fast pathway effective refractory period (FPERP) (p=0.0001). Radiofrequency ablation of the atrioventricular nodal slow pathway for AVNRT significantly reduced the effective refractory period of the fast pathway from 350 ms to 290 ms.
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