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October 24, 2000Proceedings of the National Academy of Sciences

Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+T cells

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Authors

MKMichael S. KuhnsUniversity of ArizonaVEVictoria A. EpshteynUniversity of California, San DiegoRSRaymond A. SobelDartmouth College

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Kuhns et al. (2000) studied this question.

synapsesocial.com/papers/6a1277208edbaba0bf67505ehttps://doi.org/10.1073/pnas.220423597
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Also Consider

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  2. 2Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis.1993 · 276 citations
  3. 3Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-41995 · 316 citations
  4. 4Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4 + T cell responses1999 · 116 citations
  5. 5CTLA-4-Mediated Inhibition of Early Events of T Cell Proliferation1999 · 420 citations