Key result
EVAR for ruptured abdominal aortic aneurysms is linked to ~21% higher 12-month survival versus open repair.
Why the study?
Ruptured abdominal aortic aneurysm has high mortality, and while EVAR has evolved as an alternative to open repair, comparative safety and efficacy data across long-term institutional experience were needed.
Does EVAR improve survival and reduce complications compared to open repair in patients with ruptured abdominal aortic aneurysm?
Cohort
No
Does EVAR improve survival and reduce complications compared to open repair in patients with ruptured abdominal aortic aneurysm?
EVAR is associated with lower 30-day and in-hospital mortality and better 12-month survival compared to open repair for ruptured abdominal aortic aneurysms, particularly in elderly patients.
Answers are grounded in this paper and cite their sources.
May support EVAR consideration in ruptured AAA; hypothesis-generating and requires randomized confirmation.
Objective: Ruptured abdominal aortic aneurysm (rAAA) is a critical condition with a high mortality rate. Over the years, endovascular aortic repair (EVAR) has evolved as a viable treatment option in addition to open repair (OR). The primary objective of this study was to compare the safety and efficacy of EVAR and OR for the treatment of rAAA based on a comprehensive analysis of our single-centre 30-year experience. Methods: Patients treated for rAAA at the Department of Vascular and Endovascular Surgery, University Hospital Düsseldorf, Germany from 1 January 1993 to 31 December 2022 were included. Relevant information was retrieved from archived medical records. Patient survival and surgery-related complications were analysed. Results: None of the patient-specific markers, emergency department-associated parameters, and co-morbidities were associated with patient survival. The 30-day and in-hospital mortality was higher in the OR group vs. in the EVAR group (50% vs. 8.7% and 57.1% vs. 13%, respectively). OR was associated with more frequent occurrence of more severe complications when compared to EVAR. Overall patient survival was 56 ± 5% at 12 months post-surgery (52 ± 6% for OR vs. 73 ± 11% for EVAR, respectively) (p < 0.05). Patients ≥70 years of age showed poorer survival in the OR group, with a 12-month survival of 42 ± 7% vs. 70 ± 10% for patients <70 years of age (p < 0.05). In the EVAR group, this age-related survival advantage was not found (12-month survival: ≥70 years: 67 ± 14%, <70 years: 86 ± 13%). Gender-specific survival was similar regardless of the applied method of care. Conclusion: OR was associated with more severe complications in our study. EVAR initially outperformed OR for rAAA regarding patient survival while re-interventions following EVAR negatively affect survival in the long-term. Elderly patients should be treated with EVAR. Gender does not seem to have a significant impact on survival.
No takes yet. Share an insight, caveat, or question.
Duran et al. (2023) conducted a cohort in Ruptured abdominal aortic aneurysm (rAAA). Endovascular aortic repair (EVAR) vs. Open repair (OR) was evaluated on 12-month patient survival (p=<0.05). Endovascular aortic repair for ruptured abdominal aortic aneurysm resulted in higher 12-month survival compared to open repair (73% vs 52%, p<0.05).
Synapse has enriched 10 related papers. Consider them for comparative context: