80P Correlates of inflammation in young-onset breast cancer survivors

May 1, 2026ESMO OpenOpen Access

View Full Paper

Ask AI

Bookmark

Share

Key Points

This study aims to investigate the association of DSC2 levels with inflammation and clinical outcomes in young-onset breast cancer survivors.
Samples collected from the GeparQuinto (NCT00567554) and GeparSixto (NCT01426880) trials.
Multivariate analysis was performed to assess the association of DSC2 with overall survival and other outcomes.
Investigated differences in DSC2 levels among patients with varying metastasis types.
High DSC2 levels correlated with worse overall survival (HR 2.41, 95% CI 1.44-4.02, p=0.005).
No significant association was found between DSC2 and the first site of distant metastasis.
DSC2 levels were statistically significant in predicting non-CNS metastasis in the luminal B subgroup.

Investigates inflammation markers and outcomes in young-onset breast cancer survivors, suggesting implications for prognosis.

No abstract yet. The journal hasn't published one we can show.

No takes yet. Share an insight, caveat, or question.

Brantley et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

Share