PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
May 24, 2026BioengineeringOpen Access

Chitosan-Modified Gold Nanoparticle-Based Electrochemical Immunosensor for C-Reactive Protein Detection

View Full Paper
Ask AI
Bookmark
Share

Authors

BABilal AhmadCQChangyun QuanXZXiyue Zhang

Discussion

Loading...

Member takes

Overview

Randomized trial demonstrates effective C-reactive protein detection in inflammatory conditions, suggesting promising POC applications.

Key Points

  • This research aims to develop a sensitive electrochemical immunosensor for the detection of C-reactive protein (CRP), a key inflammation biomarker.
  • Developed a chitosan-modified electrochemical immunosensor using gold nanoparticles on a screen-printed carbon electrode.
  • Optimized electrode conditions with self-assembled monolayer and antibody immobilization.
  • Characterized electrochemical performance using cyclic voltammetry, impedance spectroscopy, and differential pulse voltammetry.
  • Achieved a low limit of detection (LOD) of 0.16 µg/mL and a linear detection range of 5–100 µg/mL.
  • Demonstrated high selectivity against 13 potential interferents and good reproducibility with a relative standard deviation (RSD) of 3.69%.
  • Maintained over 95% signal stability after 15 days and 97% regeneration efficiency over seven cycles.

Cite This Study

Ahmad et al. (2026) studied this question.

synapsesocial.com/papers/6a12965848a0ea16656731b1https://doi.org/10.3390/bioengineering13060592
View Full Paper
Ask AI
Bookmark
Share