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Introduction: Alzheimer's disease (AD) is the most common cause of dementia worldwide. Mild cognitive impairment (MCI) is often the prodromal stage to AD. Most patients with MCI harbor the pathologic changes of AD and demonstrate transition to AD at a rate of 10-15% per year. Accumulating evidence indicates that the asymmetry changes of left and right brain have happened in the early stage of AD. However, the features of asymmetry changes in anterior cingulate cortex (ACC) is still unclear.
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Saatchian et al. (2020) studied this question.
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