We have investigated the dimyristoylphosphatidylcholine system with a high concentration of butanol (two molecules per phospholipid) via X-ray diffraction, differential scanning calorimetry and density measurements. A lowering of the main transition temperature for the membrane/alcohol system has been observed. The phospholipid bilayer/alcohol system is characterised by a higher density value than the pure membrane, as determined by volumetric measurements. Analysis of diffraction patterns has shown the existence of a more packed structure due to the presence of alcohol. The area of polar head has also been estimated.
No takes yet. Share an insight, caveat, or question.
Rifici et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: