Key result
Greater area-level socioeconomic deprivation is linked to ~3% higher AF prevalence per deprivation decile.
Why the study?
To examine the association of AF prevalence with neighborhood deprivation in a large, national US population across racial and ethnic groups.
Is area-level socioeconomic deprivation associated with a higher prevalence of atrial fibrillation across racial and ethnic groups in a large US population?
Cross-Sectional (n=54,487,100)
Yes
Is area-level socioeconomic deprivation associated with a higher prevalence of atrial fibrillation across racial and ethnic groups in a large US population?
Higher area-level socioeconomic deprivation is independently associated with increased atrial fibrillation prevalence across all racial and ethnic groups in the US.
Objective To examine the association of atrial fibrillation (AF) prevalence with neighborhood deprivation in a large, national U.S. population across racial and ethnic groups and its association. Methods We analyzed data from Epic Cosmos, comprising over 56 million adults with demographic and area deprivation index data in 2024. AF prevalence was defined using ICD-10 codes. Results Overall AF prevalence was 3.7%, higher in men and older adults. Prevalence varied by race/ethnicity, highest in White and American Indian/Alaska Native individuals, and lowest in Asian and Hispanic individuals. AF prevalence increased with higher deprivation across most groups. Conclusion Area-level socioeconomic deprivation was independently associated with higher AF prevalence across all racial and ethnic groups. These findings underscore the importance of addressing structural determinants of health to reduce the burden of AF in diverse communities.
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Alonso et al. (2025) conducted a cross-sectional in Atrial fibrillation (n=54,487,100). Higher Area Deprivation Index (ADI) vs. Lower Area Deprivation Index (ADI) was evaluated on Atrial fibrillation prevalence per one decile increase in Area Deprivation Index (White individuals) (PR 1.028, 95% CI 1.027-1.028). Higher area-level socioeconomic deprivation was independently associated with increased atrial fibrillation prevalence across all racial and ethnic groups, including a 3% increase per deprivation decile in White individuals (PR 1.028).
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