HIV-related stigma and academic outcomes: the mediating role of mental health among adolescents living with HIV in Uganda

December 29, 2025AIDS Care

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Key Points

To assess how mental health mediates the relationship between HIV-related stigma and academic outcomes among adolescents living with HIV.
Clinical trial registered under identifier NCT05307250.
Conducted among adolescents living with HIV in Uganda.
Evaluated the pathways connecting HIV-related stigma, psychological wellbeing, and school outcomes.
HIV-related stigma is negatively associated with academic performance through its adverse effects on mental health.
Detailed effect estimates, odds ratios, and p-values were not reported in the brief registry summary.

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Demonstrates the mediating role of mental health between HIV stigma and academic outcomes in adolescents, indicating key targets for intervention.

ClinicalTrials.gov NCT05307250; https://clinicaltrials.gov/ct2/show/NCT05307250.

Mutumba et al. (2025) studied this question.

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