High intensity interval training increased O2P slope by 22% in coronary heart disease patients, compared to a 2% increase with moderate continuous training and a 20% decrease in controls (P=0.03).
RCT (n=71)
randomly assigned
Does high intensity interval training improve markers of ventilatory and cardiac efficiency compared to moderate continuous training or no exercise in patients with coronary heart disease?
High intensity interval training is more effective than moderate continuous training for improving oxygen pulse slope in patients with coronary heart disease.
Tasa de eventos absoluta: 22% vs 2%
valor p: p=<0.05
BACKGROUND: We tested the hypothesis that high intensity interval training (HIIT) would be more effective than moderate intensity continuous training (MIT) to improve newly emerged markers of cardiorespiratory fitness in coronary heart disease (CHD) patients, as the relationship between ventilation and carbon dioxide production (VE/VCO2 slope), oxygen uptake efficiency slope (OUES), and oxygen pulse (O2P). METHODS: Seventy-one patients with optimized treatment were randomly assigned into HIIT (n = 23, age = 56 ± 12 years), MIT (n = 24, age = 62 ± 12 years), or nonexercise control group (CG) (n = 24, age = 64 ± 12 years). MIT performed 30 min of continuous aerobic exercise at 70-75% of maximal heart rate (HRmax), and HIIT performed 30 min sessions split in 2 min alternate bouts at 60%/90% HRmax (3 times/week for 16 weeks). RESULTS: No differences among groups (before versus after) were found for VE/VCO2 slope or OUES (P > 0.05). After training the O2P slope increased in HIIT (22%, P 0.05), while decreased in CG (-20%, P < 0.05) becoming lower versus HIIT (P = 0.03). CONCLUSION: HIIT was more effective than MIT for improving O2P slope in CHD patients, while VE/VCO2 slope and OUES were similarly improved by aerobic training regimens versus controls.
Cardozo et al. (Thu,) conducted a rct in Coronary heart disease (n=71). High intensity interval training (HIIT) vs. Moderate intensity continuous training (MIT) and nonexercise control group was evaluated on O2P slope (p=<0.05). High intensity interval training increased O2P slope by 22% in coronary heart disease patients, compared to a 2% increase with moderate continuous training and a 20% decrease in controls (P=0.03).