Key result
High hs-mGPS predicts ~360% higher in-hospital mortality risk in elderly NSTEMI patients.
Why the study?
Inflammation and malnutrition are poor prognostic markers in acute coronary syndromes, but the association between high sensitive modified Glasgow prognostic score and in-hospital mortality in elderly NSTEMI patients was uninvestigated.
Does a high high-sensitivity modified Glasgow prognostic score (HS-mGPS) predict increased in-hospital mortality in elderly patients with NSTEMI?
Cohort (n=282)
Yes
Does a high high-sensitivity modified Glasgow prognostic score (HS-mGPS) predict increased in-hospital mortality in elderly patients with NSTEMI?
Effect estimate: HR 4.602 (95% CI 1.581-13.391)
Absolute Event Rate: 21.8% vs 3.2%
p-value: p=0.005
The high-sensitivity modified Glasgow prognostic score (HS-mGPS) is a simple, inflammation-based tool that independently predicts in-hospital mortality in elderly patients presenting with NSTEMI.
May support HS-mGPS for mortality risk stratification in elderly NSTEMI; leaves open prospective validation before clinical adoption.
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Asarcıklı et al. (2022) conducted a cohort in Non-ST Elevation Myocardial Infarction (NSTEMI) (n=282). High high-sensitivity modified Glasgow prognostic score (HS-mGPS ≥1) vs. Low HS-mGPS (0) was evaluated on In-hospital mortality (HR 4.602, 95% CI 1.581-13.391, p=0.005). A high high-sensitivity modified Glasgow prognostic score (≥1) independently predicted a higher risk of in-hospital mortality (HR 4.602) compared to a score of 0 in elderly patients with NSTEMI.
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