Key result
Proctectomy for rectal cancer in low-volume hospitals was associated with higher 90-day postoperative mortality compared to high-volume centers (OR 2.1; 95% CI 1.71-2.58; P<0.001).
Why the study?
Does high hospital volume reduce 90-day postoperative mortality in patients undergoing proctectomy for rectal cancer compared to low or intermediate volume centers?
Population
45,569 patients undergoing proctectomy for rectal cancer from 2012 to 2016 identified in the French…
Comparison
Proctectomy in high hospital volume centers vs Proctectomy in low and intermediate hospital…
Design
Cohort
Follow-up
90 days
Authors
Loading...
Low-volume proctectomy was associated with higher mortality; leaves open whether centralization improves rectal cancer outcomes.
Cohort (n=45,569)
Yes
Does high hospital volume reduce 90-day postoperative mortality in patients undergoing proctectomy for rectal cancer compared to low or intermediate volume centers?
Effect estimate: OR 2.1 (95% CI 1.71-2.58)
Absolute Event Rate: 5.6% vs 1.9%
p-value: p=<0.001
Postoperative mortality after proctectomy for rectal cancer is strongly associated with hospital volume independent of patients' comorbidities, suggesting rectal surgery should be centralized.
Amrani et al. (2018) conducted a cohort in Rectal cancer (n=45,569). Low hospital volume (<10 cases/yr) vs. High hospital volume (≥41 cases/yr) was evaluated on 90-day postoperative mortality (OR 2.1, 95% CI 1.71-2.58, p=<0.001). Proctectomy for rectal cancer in low-volume hospitals was associated with higher 90-day postoperative mortality compared to high-volume centers (OR 2.1; 95% CI 1.71-2.58; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: