Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Organization of plasma membrane functional rafts upon T cell activation2001 · 138 citations
2. 2Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.1994 · 500 citations
3. 3Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition1992 · 156 citations
4. 4Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry.1986 · 365 citations
5. 5Cutting Edge: Fyn Is Essential for Tyrosine Phosphorylation of Csk-Binding Protein/Phosphoprotein Associated with Glycolipid-Enriched Microdomains in Lipid Rafts in Resting T Cells2002 · 126 citations