Key result
Young ischemic stroke patients with 0 to 5 risk factors had later vascular event rates of 2.1% to 67% (p<0.001), suggesting those with 0 factors may not need preventive medication.
Young ischemic stroke patients with no traditional risk factors have a very low rate of recurrent vascular events, suggesting long-term secondary preventive medication may not be necessary for this specific subgroup.
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Should not yet alter secondary prevention in young stroke without risk factors; hypothesis-generating for targeted deprescribing trials.
After a mean of 6 years, the frequencies of later vascular events (recurrent ischemic stroke or myocardial infarction) in 232 young ischemic stroke patients (younger than 50 years) with none to five traditional risk factors were 2.1%, 6%, 19%, 26%, 30%, and 67% (p < 0.001). Long-term secondary preventive medication may not be indicated in young ischemic stroke patients with no risk factor.
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Næss et al. (2005) studied this question. Young ischemic stroke patients with 0 to 5 risk factors had later vascular event rates of 2.1% to 67% (p<0.001), suggesting those with 0 factors may not need preventive medication.
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