What question did this study set out to answer?

Determine whether nutritional deprivation alone contributes to the reduction of urinary 17-ketosteroid excretion observed during human disease.

February 1, 1948The Journal of Clinical Endocrinology & Metabolism

The Effect of Starvation on Urinary 17-Ketosteroid Excretion*

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Authors

RLRichard L. LandauMassachusetts Institute of Technology KKKathryn KnowltonNational Institutes of Health DADolores Anderson

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Implication

Experimental study reveals reduced urinary 17-ketosteroid excretion during fasting in adults, indicating that undernutrition independently suppresses androgen output.

Key Points

Determine whether nutritional deprivation alone contributes to the reduction of urinary 17-ketosteroid excretion observed during human disease.
Assessed total starvation in three healthy men and one obese woman.
Evaluated mild protein and caloric restriction in two healthy men.
Starvation and caloric restriction independently depress urinary 17-ketosteroid excretion in healthy and obese subjects.
Depressed excretion occurs in the absence of acute infection or tissue trauma, reflecting inanition-induced suppression of testicular androgen production.

Cite This Study

Landau et al. (1948) studied this question.

synapsesocial.com/papers/6a12f339b761793c20c0dc4e https://doi.org/10.1210/jcem-8-2-133

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Implication

Experimental study reveals reduced urinary 17-ketosteroid excretion during fasting in adults, indicating that undernutrition independently suppresses androgen output.

The Effect of Starvation on Urinary 17-Ketosteroid Excretion*

Discussion

Member takes

Implication

Key Points

Cite This Study

The Effect of Starvation on Urinary 17-Ketosteroid Excretion*

Discussion

Member takes

Implication

Key Points

Cite This Study

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