Why the study?
Does anticoagulant therapy cause hemopericardium without myocardial rupture in patients with myocardial infarction?
Does anticoagulant therapy cause hemopericardium without myocardial rupture in patients with myocardial infarction?
Highlights the risk of fatal hemopericardium without myocardial rupture in patients receiving anticoagulant therapy for myocardial infarction.
Answers are grounded in this paper and cite their sources.
Demands vigilant anticoagulation monitoring in acute MI; confirms hemopericardium risk independent of rupture.
A DISTURBING feature of the occasional case of fatal hemopericardium following anticoagulant therapy for myocardial infarction is the absence of an obvious explanation for the hemorrhage. Heretofore, a pericardium distended with blood in a patient with myocardial infarction has usually been the result of a ruptured myocardium. However, Hammarsten1 reported in 1949 a case with massive hemopericardium that followed Dicumarol treatment in which low levels of prothrombin activity (10 per cent or less) were obtained; 800 cc. of blood was found in the pericardium and yet no rupture of the heart or a vessel could be demonstrated. Nichol,2 Goldstein and . . .
No takes yet. Share an insight, caveat, or question.
Waldron et al. (1954) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: