Key result
In Indian ICU patients with major surgeries or injuries receiving no mechanical or chemical prophylaxis, the incidence of deep vein thrombosis was 6.6%, with no cases of pulmonary embolism.
Observational (n=150)
No
The low incidence of DVT (6.6%) and absence of pulmonary embolism in Indian patients undergoing major surgery or trauma suggests that routine chemoprophylaxis may not be justified for all patients in this population.
May question routine prophylaxis in Indian surgical/trauma ICU patients; hypothesis-generating and requires RCT confirmation.
Venous thromboembolism (VTE) is considered a major health problem in western countries necessitating thromboprophylaxis. Only a few studies are available regarding incidence in Indian patients resulting in uncertainty regarding thromboprophylaxis for our patients. In our prospective study over a period of 3 years we studied 150 patients (average age 55 years) to determine the incidence of Deep Vein Thrombosis (DVT). These patients were admitted in ICU who remained bedridden for many days and were observed for atleast four weeks. No mechanical or chemical form of deep venous thrombosis prophylaxis was used. All the patients underwent duplex ultrasonography between 7th and 14th postoperative day. None of the patients developed pulmonary embolism (PE). DVT developed in only 10 patients (6.6%). In India there is much lower incidence of DVT as compared to western countries.
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Angral et al. (2012) conducted an observational in ICU patients with major surgeries or injuries (n=150). No DVT prophylaxis was evaluated on Incidence of Deep Vein Thrombosis (DVT). In Indian ICU patients with major surgeries or injuries receiving no mechanical or chemical prophylaxis, the incidence of deep vein thrombosis was 6.6%, with no cases of pulmonary embolism.
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