Key result
Nebivolol was associated with a lower incidence of erectile dysfunction compared to metoprolol succinate in patients following coronary artery bypass surgery (83.87% vs 85.96%; p=0.036).
Why the study?
Does nebivolol improve erectile dysfunction compared to metoprolol succinate in sexually active male patients following coronary artery bypass surgery?
Observational (n=119)
No
Does nebivolol improve erectile dysfunction compared to metoprolol succinate in sexually active male patients following coronary artery bypass surgery?
In sexually active men undergoing coronary artery bypass surgery, nebivolol use is associated with significantly better erectile function scores compared to metoprolol succinate, without compromising anti-ischemic efficacy.
Supports nebivolol over metoprolol post-CABG to lower ED incidence; extends beta-blocker comparisons to cardiac surgery patients.
PURPOSE: Beta-blocker use is common in the cases with coronary artery bypass surgery. According to the literature, beta-blockers have positive effects but may cause erectile dysfunction (ED). The most commonly used beta-blockers in ischemic cardiac disease are nebivolol and metoprolol. In our clinic, we aimed to compare the effects of nebivolol and metoprolol succinate on ED in the sexually active cases with coronary artery bypass surgery. METHODS: In our clinic, a total of 119 patients with coronary artery bypass surgery were included in the study. International Index of Erectile Function (IIEF-5) Test was used to evaluate whether the patients had ED and to grade the cases. RESULTS: No significant difference was found in terms of anti-ischemic efficacy between metoprolol succinate and nebivolol in the postoperative period; however, the incidence of any grade ED was %85.96 in Group 1, %83.87 in Group 2. This difference was considered as statistically significant (p = 0.036). CONCLUSION: Beta-blocker use increases the risk of ED in cases with ischemic cardiac disease. We suggest that the complaints of ED could be less frequent with nebivolol use in sexually active cases with ischemic cardiac disease.
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Gür et al. (2017) conducted an observational in Coronary artery bypass surgery (n=119). Nebivolol vs. Metoprolol succinate was evaluated on Incidence of any grade erectile dysfunction (ED) (p=0.036). Nebivolol was associated with a lower incidence of erectile dysfunction compared to metoprolol succinate in patients following coronary artery bypass surgery (83.87% vs 85.96%; p=0.036).
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