Why the study?
The study aimed to evaluate the role of the triglyceride glucose index in predicting and mediating the development of cardiovascular disease.
Does a higher triglyceride glucose (TyG) index predict the development of cardiovascular events in adults aged over 60 years?
Population
6078 participants aged over 60 years in a routine health check-up programme
Comparison
Higher vs lower TyG index quartiles
Design
Retrospective cohort study
Follow-up
Median 6 years
Key result
The highest quartile of the triglyceride glucose index was associated with a significantly increased risk of cardiovascular disease events compared to the lowest quartile (SHR 1.72).
Authors
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TyG index may aid CVD risk identification in older adults; leaves open its added value beyond standard predictors.
Cohort (n=6,078)
Yes
Does a higher triglyceride glucose (TyG) index predict the development of cardiovascular events in adults aged over 60 years?
Effect estimate: SHR 1.72 (95% CI 1.37-2.16)
Absolute Event Rate: 18.37% vs 7.94%
p-value: p=<0.001
A higher triglyceride glucose (TyG) index is significantly associated with an increased risk of cardiovascular events in older adults, suggesting its utility as a predictive biomarker.
Li et al. (2019) conducted a cohort in Cardiovascular disease (n=6,078). Triglyceride glucose (TyG) index (Quartile 4) vs. Triglyceride glucose (TyG) index (Quartile 1) was evaluated on Cardiovascular disease (CVD) events (SHR 1.72, 95% CI 1.37-2.16, p=<0.001). The highest quartile of the triglyceride glucose index was associated with a significantly increased risk of cardiovascular disease events compared to the lowest quartile (SHR 1.72).