Key result
Live 3D TTE measurements of vena contracta area correlated better with aortographic or surgical grading of aortic regurgitation (r = 0.95) than 2D TTE measurements of vena contracta width (r = 0.92).
Why the study?
Does live 3D TTE measurement of vena contracta area improve the accuracy of aortic regurgitation assessment compared to 2D TTE when validated against aortography or surgery in adult patients?
Observational (n=56)
Does live 3D TTE measurement of vena contracta area improve the accuracy of aortic regurgitation assessment compared to 2D TTE when validated against aortography or surgery in adult patients?
Effect estimate: r = 0.95
Live 3D TTE measurement of vena contracta area provides highly accurate assessment of aortic regurgitation severity, correlating better with invasive reference standards than standard 2D TTE.
May aid aortic regurgitation grading; extends mitral regurgitation 3D vena contracta work but remains hypothesis-generating.
In this report, we evaluate 56 consecutive adult patients who underwent standard two-dimensional (2D) and live three-dimensional transthoracic echocardiography (3D TTE), as well as left heart catheterization with aortography (45 patients) or cardiac surgery (11 patients), for evaluation of aortic insufficiency. Similar to the method we previously described for mitral insufficiency, aortic regurgitant vena contracta area (VCA) was obtained by 3D TTE by systematic and sequential cropping of the acquired 3D TTE data set. Assessments of aortic regurgitation (AR) by aortography and surgery are compared to measurements of VCA by 3D TTE and to 2D TTE measurements of vena contracta width (VCW). Aortographic or surgical grading correlated well with 2D TTE measurements of VCW (r = 0.92), but correlated better with 3D TTE measurements of VCA (r = 0.95), with improved dispersion between angiographic grades demonstrated by the 3D TTE technique. Live 3D TTE color Doppler measurements of VCA can be used for accurate assessment of AR and are comparable to assessment by aortography.
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Fang et al. (2005) conducted an observational in Aortic regurgitation (n=56). Live 3D TTE measurements of vena contracta area vs. 2D TTE measurements of vena contracta width and aortography/surgery was evaluated on Correlation with aortographic or surgical grading of aortic regurgitation (r = 0.95). Live 3D TTE measurements of vena contracta area correlated better with aortographic or surgical grading of aortic regurgitation (r = 0.95) than 2D TTE measurements of vena contracta width (r = 0.92).
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