Key result
SCAD in COVID-19 patients shows 100% survival without cardiovascular complications.
Why the study?
Spontaneous coronary artery dissection presents a unique clinical challenge requiring rapid diagnosis and treatment, motivating a comprehensive review of SCAD cases in patients with COVID-19.
Systematic Review (n=12)
SCAD in COVID-19 patients predominantly affects middle-aged women and has favorable outcomes with appropriate conservative or interventional management, similar to non-COVID-19 SCAD.
Supports standard SCAD management in COVID-19; extends sparse case data but leaves open true incidence and causality.
Kontext: SpontĂĄnnĂ disekce koronĂĄrnĂ tepny (spontaneous coronary artery dissection, SCAD) pĹedstavuje unikĂĄtnĂ medicĂnskou vĂ˝zvu vzhledem k nutnosti rychle stanovit diagnĂłzu a zahĂĄjit lĂŠÄbu; vyĹžaduje pĹitom velmi dobrou znalost zĂĄkladnĂch mechanismĹŻ. CĂlem tohoto systematickĂŠho pĹehledovĂŠho ÄllĂĄnku je nabĂdnout komplexnĂ pĹehled pĹĂpadĹŻ SCAD u pacientĹŻ s diagnĂłzou onemocnÄnĂ covid-19. Metody: Dne 3. Äervna 2023 jsme provedli systematickĂ˝ pĹehled ÄlĂĄnkĹŻ v databĂĄzĂch vÄetnÄ PubMed, ScienceDirect a Cochrane. Do pĹehledu jsme zahrnuli pĹĂpady SCAD u pacientĹŻ s onemocnÄnĂm covid-19, v nichĹž byly uvedeny Ăşdaje jednotlivĂ˝ch pacientĹŻ. VĂ˝sledky: Studie analyzovala 12 kazuistik; u vĹĄech pacientĹŻ byla potvrzena diagnĂłza onemocnÄnĂ covid-19, byli ve vÄku s mediĂĄnem 49 let, jednalo se pĹevĂĄĹžnÄ o Ĺženy (58,3 %). VÄtĹĄina pacientĹŻ vykazovala klasickĂŠ symptomy onemocnÄnĂ covid-19 (66,7 %), pĹiÄemĹž tÄĹžkĂŠ projevy byly pozorovĂĄny u pacientek s tÄhotenstvĂm v anamnĂŠze. Äasto byly zaznamenĂĄny vysokĂŠ hodnoty troponinĹŻ (83,3 %) stejnÄ jako zmÄny na EKG zĂĄznamu, hlavnÄ abnormality v Ăşseku ST a vlnÄ T. HlavnĂm diagnostickĂ˝m nĂĄstrojem byla koronagrafie (91,7 %), pĹiÄemĹž neÄastÄjĹĄĂm mĂstem disekce byla pĹednĂ sestupnĂĄ vÄtev levĂŠ vÄnÄitĂŠ tepny (50 %). Ve ÄtyĹech pĹĂpadech byla zjiĹĄtÄna snĂĹženĂĄ ejekÄnĂ frakce levĂŠ komory, ale po lĂŠÄbÄ nebyly zaznamenĂĄny ŞådnĂŠ kardiovaskulĂĄrnĂ komplikace. ZĂĄvÄr: Tato studie popisuje charakteristiky SCAD u pacientĹŻ s infekÄnĂm onemocnÄnĂm covid-19; zĂĄroveĹ byly pozorovĂĄny vhodnĂŠ diagnostickĂŠ postupy a lĂŠÄebnĂŠ strategie.
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Andrianto et al. (2025) conducted a systematic review in Spontaneous Coronary Artery Dissection (SCAD) with COVID-19 (n=12). In a systematic review of 12 cases, spontaneous coronary artery dissection in COVID-19 patients predominantly affected females (58.3%) and all patients survived without cardiovascular complications.
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