Key result
A review of studies on moderate aortic stenosis highlights factors increasing disease progression and proposes an ideal trial design using modern tools like strain and magnetic resonance imaging.
This viewpoint highlights the higher mortality in moderate aortic stenosis and proposes a trial design using advanced imaging to evaluate disease progression factors.
Moderate aortic stenosis warrants closer surveillance given its mortality burden; leaves open optimal trial designs incorporating strain and CMR to clarify progression.
Aortic stenosis (AS) is the most frequent valvular heart disease encountered in our daily practice. Although there are clear guidelines for severe AS management, cardiologists often have few treatment options for patients with moderate AS; however, there is higher mortality in this patient subgroup versus an age-matched population. The authors reviewed all of the studies on moderate AS, summarized the factors that increase disease progression and discussed an ideal trial design to prospectively evaluate AS progression factors using modern cardiology tools such as strain and magnetic resonance imaging.
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Mischie et al. (2012) conducted a review in Moderate Aortic Stenosis. A review of studies on moderate aortic stenosis highlights factors increasing disease progression and proposes an ideal trial design using modern tools like strain and magnetic resonance imaging.
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