Key result
Microscopic examination of a fatal postpartum coronary artery dissection case and six controls revealed no generalized arterial changes, suggesting a focal degenerative process is the most likely cause.
Why the study?
What are the morphological changes in the coronary artery wall associated with fatal postpartum spontaneous coronary artery dissection?
Population
1 fatal case of spontaneous coronary artery dissection in a 37-year-old postpartum female, and 6 postpartum…
Comparison
Pathological examination using light, scanning… vs Arterial wall samples from 6 postpartum females…
Design
Case_report
Authors
Loading...
Focal midmedia degeneration may underlie fatal postpartum SCAD; leaves open generalizability and mechanisms in larger series.
Case Report (n=7)
What are the morphological changes in the coronary artery wall associated with fatal postpartum spontaneous coronary artery dissection?
Pathological examination of a fatal postpartum spontaneous coronary artery dissection case suggests the dissection originates in the midmedia due to a focal degenerative process rather than generalized arterial changes.
Sage et al. (1986) conducted a case report in Spontaneous coronary artery dissection (n=7). Microscopic examination (LM, SEM, TEM) vs. Postpartum females who died of unrelated causes was evaluated on Morphological changes in the arterial wall. Microscopic examination of a fatal postpartum coronary artery dissection case and six controls revealed no generalized arterial changes, suggesting a focal degenerative process is the most likely cause.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: