Key result
Autoimmune diseases frequently cause insidious cardiac damage like HF and arrhythmias, demanding early detection.
Why the study?
Early cardiac manifestations in autoimmune diseases are often overlooked due to insidious or atypical features, leading to potentially severe, irreversible, and life-threatening damage once symptoms appear.
Cardiac involvement is a common but often overlooked complication in systemic autoimmune diseases, necessitating early detection and management to prevent severe and irreversible damage.
Answers are grounded in this paper and cite their sources.
May support earlier cardiac evaluation in autoimmune diseases; leaves open optimal screening protocols pending prospective studies.
Autoimmune diseases are diseases that cause damage to the body's own tissues as a result of immune dysfunction, often involving multiple organs and systems. The heart is one of the common target organs of autoimmune diseases. The whole structure of the heart can be affected, causing microcirculatory disorders, arrhythmias, pericardial damage, myocarditis, myocardial fibrosis, and impaired valvular function. However, early clinical manifestations of autoimmune heart damage are often overlooked because they are insidious or have no typical features. The damage is often severe and irreversible when symptoms are apparent, even life-threatening. Therefore, early detection and treatment of heart damage in autoimmune diseases is particularly important. Herein, we review the clinical features and mechanisms of cardiac damage in common rheumatic diseases.
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Pan et al. (2022) conducted a review in Autoimmune diseases. Autoimmune diseases frequently cause insidious but severe cardiac damage, including heart failure, pericarditis, myocarditis, and arrhythmias, necessitating early detection and treatment.
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