Retrospective study explores alternative medicine use and its association with cancer outcomes in patients.
Objective: To investigate the prevalence, utilisation and association of diagnostic delay, tumour stage andrecurrence with alternative medicine among head and neck cancer patients having undergone surgical resection.Method: The retrospective, cross-sectional study was conducted from March to June 2024 at the Department ofOtolaryngology and Head and Neck Surgery, Aga Khan University Hospital, Karachi, and comprised adult patientswho underwent surgical resection of primary head and neck cancers from January 1, 2017, to January 31, 2019. Datawas collected from the patient electronic medical records related to tumour characteristics along with detailsregarding treatment and exposure to alternative therapy. Data was analysed using SPSS 23.Results: Of the 125 patients with mean age 46.71±12.6 years, 98(78.4%) were male and 27(21.6%) were female.Overall, 33(26.4%) patients reported AM exposure. Most patients presented with advanced-stage disease 98(83.4%),and 28(28.6%) of them had sought alternative treatments prior to conventional medical care. Majority of patientshad an undergraduate education 92(86.6%), were minimum wage earners 114(91.2%), and an early recurrence wasnoted in 59(47%) cases. There was no significant difference with respect to cancer stage, levels of education andincome, and recurrence rate between those who sought alternative medicine and thoe who did not (p>0.05).Conclusion: A significant number of oral cancer patients had utilised alternative medicine. However, the practicewas not correlated with disease severity, socioeconomic status or disease recurrence.
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Akhtar et al. (2026) studied this question.
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