Rare Variant of a Rare Anomaly: Stenotic Persistent Right-Sided Fifth Aortic Arch with Fourth Arch Interruption

Alqasem Al Mosa; Michelle Noga; Luke Eckersley; Darren H. Freed

doi:10.1016/j.case.2026.03.009

May 1, 2026CASEOpen Access

Rare Variant of a Rare Anomaly: Stenotic Persistent Right-Sided Fifth Aortic Arch with Fourth Arch Interruption

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Key Points

To report a rare case of persistent fifth aortic arch with fourth aortic arch interruption and its implications.
Description of an unusual case of persistent fifth aortic arch (PFAA) with right-sided stenosis and fourth arch interruption.
Review of the literature for prior cases of right-sided PFAA.
Only 104 cases of persistent fifth aortic arch have been documented since 1969, highlighting its rarity.
This case represents a unique right-sided variant contributing to the limited knowledge of PFAA.

Implication

Case report uncovers persistent fifth aortic arch anomaly with fourth arch interruption, suggesting unique characteristics.

Abstract

Persistent fifth aortic arch (PFAA) is a very rare anomaly, with an estimated incidence of 0.01%.1 From the initial description in 1969 until 2023, only 104 cases have been reported in the literature,2,3 and few of those have been right-sided PFAA.4-6

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Cite This Study

Mosa et al. (2026) studied this question.

synapsesocial.com/papers/6a13e6b30e02ee3982d31875 https://doi.org/10.1016/j.case.2026.03.009

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Rare Variant of a Rare Anomaly: Stenotic Persistent Right-Sided Fifth Aortic Arch with Fourth Arch Interruption

Key Points

Implication

Abstract

Discussion

Cite This Study

Rare Variant of a Rare Anomaly: Stenotic Persistent Right-Sided Fifth Aortic Arch with Fourth Arch Interruption

Key Points

Implication

Abstract

Discussion

Cite This Study

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