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Phylogenetic analyses reveal Tne5, a new family of NAD(P) glycohydrolases in antagonistic systems, suggesting extensive distribution.
into nicotinamide and ADP-ribose. Phylogenetic analyses and structural modeling show that this effector defines a new ART-related family of NAD(P) glycohydrolases broadly distributed across antagonistic systems, which we propose to name Tne5.
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Desjardins et al. (2026) studied this question.
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