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May 25, 2026Molecular and Cellular Biology0 citationsOpen Access

The Yeast AP-1 Factor Yap8 Recruits SAGA and SWI/SNF to Regulate ACR3 Expression and Arsenic Tolerance

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EMEwa Maciaszczyk-DziubińskaUniversity of WrocławARAntonia M. RomeroConsejo Superior de Investigaciones CientíficasNKNallani Vijay KumarUniversity of Gothenburg

Key Points

  • This research investigates the role of the Yap8 protein in regulating arsenic tolerance through ACR3 expression.
  • Utilized molecular techniques to analyze Yap8 function in yeast.
  • Examined recruitment of SAGA and SWI/SNF complexes to target genes.
  • Assessed the impact of Yap8 on arsenic tolerance.
  • Yap8 significantly enhances ACR3 expression, leading to increased arsenic tolerance.
  • Recruitment of SAGA and SWI/SNF by Yap8 is crucial for this regulation.

Abstract

The AP-1-like protein Yap8 is required for arsenic tolerance in the yeast

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Cite This Study

Maciaszczyk-Dziubińska et al. (2026) studied this question.

synapsesocial.com/papers/6a13e7e80e02ee3982d32894https://doi.org/10.1080/10985549.2026.2671974
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Yap, a Novel Family of Eight bZIP Proteins in Saccharomyces cerevisiae with Distinct Biological Functions1997 · 317 citations
  2. 2Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae1998 · 5,571 citations
  3. 3Identification of SWI·SNF Complex Subunit BAF60a as a Determinant of the Transactivation Potential of Fos/Jun Dimers2001 · 169 citations
  4. 4A quantitative model of transcription factor–activated gene expression2008 · 154 citations
  5. 5Transcriptional Profiling Shows that Gcn4p Is a Master Regulator of Gene Expression during Amino Acid Starvation in Yeast2001 · 768 citations