Integrated review demonstrates shared principles of machine perfusion in organs, highlighting cross-organ therapy evaluation opportunities.
• Machine perfusion aims to reduce ischemia-reperfusion injury (IRI) and test function • Fundamental pathophysiological processes underlying IRI are shared across organs • Clinical machine perfusion trials are often considered in organ-specific silos • This integrated review highlights consistent trial findings across organ types • Cross-organ learning offers opportunities to prioritise therapies for evaluation
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Tingle et al. (2026) studied this question.
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