Key result
Qualitative lesion assessment correlates more strongly with clinical plans than standard percent diameter stenosis.
Why the study?
Given imperfections in reporting coronary lesion severity using percent diameter stenosis and the availability of intracoronary imaging and physiology, a simpler and more clinically relevant qualitative lesion assessment system was evaluated.
Does a qualitative lesion assessment system correlate better with the chosen clinical plan than percent diameter stenosis in coronary angiography?
Observational (n=100)
Does a qualitative lesion assessment system correlate better with the chosen clinical plan than percent diameter stenosis in coronary angiography?
p-value: p=<.01
A qualitative lesion assessment system correlates more strongly with clinical decision-making than traditional percent diameter stenosis, suggesting it could be a more clinically relevant tool for coronary angiography.
May better align lesion assessment with clinical plans than percent stenosis; hypothesis-generating from cross-sectional data and needs prospective validation.
Since the advent of coronary angiography, the standard for reporting of coronary lesion severity has been to utilize percent diameter stenosis (%DS). Given the imperfections of %DS as well as the widespread availability of intraprocedural intracoronary imaging and physiology assessment, it is time to consider a simpler yet more clinically relevant lesion assessment system. We compiled ten actual cases and presented these cases to 10 operators, providing 100 independent lesion assessments. For each case, operators were asked to describe lesions using %DS and a simplified lesion assessment system. We assessed the relationship between %DS and qualitative lesion assessment as well as the relationship of both measurements to the chosen plan. Greater variability exists with %DS than with qualitative lesion assessment. Despite this, there is good correlation between %DS and the qualitative lesion assessment (ρ = 0.8221). There remains overlap of lesion assessment using the qualitative lesion assessment tool suggesting that even with this simpler tool, there remains interobserver variability (ICC = 0.5164, 95% confidence interval [CI] 0.2924-0.7955). When assessing how both lesion assessment, there appears to be a stronger correlation between the qualitative lesion assessment and the chosen plan versus the %DS and the chosen plan (ρ = 0.9069 vs ρ = 0.8001, P < .01). Given the superior performance of the proposed qualitative system and the ability to estimate lesion severity using both anatomic and clinical factors, we feel that professional societies and clinicians should begin to embrace this simplified means of lesion assessment.
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Jones et al. (2020) conducted an observational in Coronary lesions (n=100). Qualitative lesion assessment system vs. Percent diameter stenosis (%DS) was evaluated on Correlation between lesion assessment and chosen clinical plan (p=<.01). A qualitative lesion assessment system demonstrated a stronger correlation with the chosen clinical plan compared to standard percent diameter stenosis (ρ = 0.9069 vs ρ = 0.8001, P < .01).
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