Key result
Patients with unheralded acute myocardial infarction had significantly fewer diseased coronary vessels compared to patients with uncomplicated stable angina pectoris (1.52 vs 2.37, p<0.001).
Why the study?
Does angiographic severity differ between patients presenting with unheralded acute myocardial infarction versus uncomplicated stable angina pectoris?
Cohort (n=100)
Random sampling
No
Does angiographic severity differ between patients presenting with unheralded acute myocardial infarction versus uncomplicated stable angina pectoris?
Patients presenting with unheralded acute myocardial infarction typically have less extensive coronary artery disease (fewer diseased vessels and stenoses) compared to those with chronic stable angina.
A prospective randomized cohort study was done in 100 patients and the study population consisted 50 patients with unheralded acute myocardial infarction and 50 with uncomplicated stable angina pectoris. The main objectives of the study were to compare the angiographic severity between the two clinical subsets of IHD. The study observed that regarding number of vessels diseased , the AMI group had 1.52±0.68 compared with 2.37±0.85 vessels for the angina group reflecting significantly higher diseased vessel in latter group (P<0.001). In comparison with unheralded AMI, the stable angina group had greater number of stenoses(4.16±1.9 vs 2.14±1.5, P<0.001) and also greater number of occlusions(0.80±0.65 vs 0.44±0.31, P<0.001 ). Thus from the above data it is clear that single vessel disease is more frequent in AMI group and double- and tripple vessel diseases are more prevalent in angina group and fewer stenoses and discrete type of lesions in the former and more number of diseased vessels, more stenoses, and diffuse type of lesions in the latter. DOI: http://dx.doi.org/10.3329/uhj.v8i1.11659 University Heart Journal Vol. 8, No. 1, January 2012
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Safiuddin et al. (2012) conducted a cohort in Ischemic Heart Disease (Acute Myocardial Infarction vs Stable Angina Pectoris) (n=100). Unheralded acute myocardial infarction vs. Uncomplicated stable angina pectoris was evaluated on Number of diseased vessels (p=<0.001). Patients with unheralded acute myocardial infarction had significantly fewer diseased coronary vessels compared to patients with uncomplicated stable angina pectoris (1.52 vs 2.37, p<0.001).
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