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October 9, 1967JAMA258 citations

Surgery's Relevance to an Understanding of Basic Biology

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JDJ. Englebert Dunphy

Key Points

  • The aim is to explore the relationship between surgical practices and fundamental biological processes.
  • Examined the synthesis of proteins incorporating DNA and RNA interactions.
  • Discussed historical concerns related to DNA structure and replication capabilities.
  • Identified key roles of DNA and various RNAs in protein synthesis.
  • Demonstrated the potential implications of this understanding on surgical methods.

Abstract

When J. D. Watson received the Nobel Prize in medicine in 1962, a prize which he shared with Francis Crick and Maurice Wilkins, he demonstrated in his lecture at Stockholm that the synthesis of protein1required the ordered interaction of deoxyribonucleic acid and at least three types of functional ribonucleic acid. In the introduction he tells of the anxieties and concerns which he and Crick felt when they were first trying to elucidate the structure of DNA. He wrote, During the next eighteen months, until the structure became elucidated, we frequently discussed the necessity that the correct structure have a capacity for replication and, in pessimistic moods we often worried that the structure might be dull, that it would suggest absolutely nothing and excite us no more than something inert, like collagen. Watson's view of collagen is illustrative of the powerful vision of a great mind finding a new

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Cite This Study

J. Englebert Dunphy (1967) studied this question.

synapsesocial.com/papers/6a140bb37753e742da59a6e5https://doi.org/10.1001/jama.1967.03130150084015
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