Demonstrates transient shortening of left ventricular systole during acute myocardial infarction, indicating peak mechanical dysfunction occurs within three days.
Fifty-one patients with acute myocardial infarction had serial measurements of left ventricular systolic time intervals by indirect methods. Patients were divided into Group I without left ven- tricular failure and Group 2 with left ventricular failure. Total electromechanical systole (Q-A2 interval) and left ventricular ejection time were shortened. The pre-ejection period and isovolu- metric contraction time were not significantly changed. The alterations in systolic time intervals were most conspicuous in Group 2 patients with left ventricular failure. The maximal changes occurred 2 to 3 days after acute myocardial infarction with a progressive return towards normal over a period of 3 weeks.
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Fabián et al. (1972) studied this question.
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