Association between ex vivo thrombogenicity and ischemic outcome in off-pump coronary surgery

Figures

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  Figure 1.. CONSORT diagram of the study. TEG, thromboelastography. Incorrect TEG data refers to distorted TEG graphs and values due to accidental external shaking of the apparatus.

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  Figure 2.. Association between maximal amplitude and 1-year major adverse cardiovascular events. Nonlinearity was tested using a restricted cubic spline model. The model was fitted with three knots at the maximal amplitude’s 10th, 50th, and 90th percentiles, with the median (67.6 mm) as the reference. Odds ratios (solid lines) and 95% confidence intervals (shaded areas) were estimated after adjusting for age, hypertension, diabetes mellitus, chronic kidney disease, anemia, and congestive heart failure (a) and additionally for sex, left ventricular ejection fraction, beta-blockers, renin-angiotensin system antagonists, diuretics, hemoglobin, white blood cells, platelets, fibrinogen, international normalized ratio, C-reactive protein, troponin-T, albumin, and intra-operative transfusion (b).

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  Figure 3.. Receiver operating characteristic curve for the maximal amplitude in detecting 1-year major adverse cardiovascular events. The optimal cut-off value for the maximal amplitude in detecting 1-year major adverse cardiovascular events was determined using the youden index. Abbreviations: AUC, area under the curve; CI, confidence interval.

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  Figure 4.. Kaplan-Meier curves of MACE (a) and mortality (b) according to tertiles of maximal amplitude. Abbreviation: MACE, major adverse cardiovascular events.

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  Figure 5.. Kaplan-Meier curves of major adverse cardiac events (a) and mortality (b) according to the optimal cut-off value of maximal amplitude (69.6 mm) discerning high- from the low-risk group. Abbreviation: MACE, major adverse cardiovascular events.