Key result
Age, creatinine, ejection fraction, and left atrium score predicts ~13-fold higher AF recurrence post-cryoballoon ablation.
Why the study?
The study aimed to evaluate whether integrating left atrium diameter into the age, creatinine, and ejection fraction score could predict atrial fibrillation recurrence after cryoballoon catheter ablation.
Does the ACEF-LA score predict atrial fibrillation recurrence in patients with paroxysmal or persistent atrial fibrillation undergoing cryoballoon ablation?
Cohort (n=106)
Does the ACEF-LA score predict atrial fibrillation recurrence in patients with paroxysmal or persistent atrial fibrillation undergoing cryoballoon ablation?
The ACEF-LA score is a strong independent predictor of atrial fibrillation recurrence after cryoballoon ablation, offering a potentially useful tool for risk stratification.
Answers are grounded in this paper and cite their sources.
May support pre-ablation risk stratification; leaves open prospective validation before clinical use.
BACKGROUND: Several clinical trials have assessed predictors for atrial fibrillation recurrence following cryoballoon catheter ablation. With these predictors, a practical and new scoring system can be developed to evaluate atrial fibrillation recurrence. The present study aimed to analyze the predictive value of the age, creatinine, and ejection fraction-left atrium score for potential recurrence of atrial fibrillation following cryoballoon catheter ablation in patients with symptomatic paroxysmal or persistent atrial fibrillation. METHODS: We retrospectively analyzed records of patients undergoing cryoballoon cath-eter ablation. atrial fibrillation recurrence was defined as an emerging atrial fibrillation episode around 12-month follow-up (with the exclusion of a 3-month blanking period). Univariate and multivariate analyses were performed to assess predictors of atrial fibrillation recurrence. In addition, receiver operating characteristic analysis was harnessed to evaluate the performance of the age, creatinine, and ejection fraction, left atrium score in determining the risk of atrial fibrillation recurrence. RESULTS: The study population comprised 106 subjects (age 52 ± 13 years, 63.2% women) with paroxysmal (84.9%, n = 90) or persistent (15.1%, n = 16) atrial fibrillation. age, creatinine, and ejection fraction, left atrium score was significantly higher in subjects with atrial fibrillation recurrence in comparison to those with the maintenance of sinus rhythm. However, on multivariate logistic regression analysis, only the age, creatinine, and ejection fraction, left atrium score (OR = 12.93, 95% CI: 2.22-75.21, P =.004) served as an independent predictor of atrial fibrillation recurrence following cryoballoon catheter ablation. CONCLUSION: Age, creatinine, and ejection fraction, left atrium score had an independent association with the risk of atrial fibrillation recurrence in subjects with atrial fibrillation undergoing cryoballoon catheter ablation. Therefore, this score might potentially serve as a useful tool for risk stratification of patients with atrial fibrillation.
No takes yet. Share an insight, caveat, or question.
Gökay Taylan (2023) conducted a cohort in symptomatic paroxysmal or persistent atrial fibrillation (n=106). Age, creatinine, and ejection fraction, left atrium score was evaluated on Atrial fibrillation recurrence (emerging atrial fibrillation episode around 12-month follow-up, excluding a 3-month blanking period) (OR 12.93, 95% CI 2.22-75.21, p=.004). The age, creatinine, ejection fraction, and left atrium score independently predicted atrial fibrillation recurrence following cryoballoon ablation (OR 12.93; 95% CI 2.22-75.21; P=.004).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: