Key result
A rare case of left ventricular cardiac chloroma was discovered by echocardiography and MRI in an elderly male with acute myeloid leukemia who subsequently died from intracranial hemorrhage.
Why the study?
Cardiac involvement with myeloid sarcoma is exceedingly rare.
Case Report (n=1)
Highlights a very rare presentation of cardiac myeloid sarcoma (chloroma) diagnosed via multimodality imaging in an elderly patient with acute myeloid leukemia.
May alert clinicians to rare cardiac chloroma in AML; leaves open need for systematic data on detection and outcomes.
Chloroma or myeloid sarcoma is rare extramedullary tumor composed of immature myeloid cells that may occur in association with or during or even before the course of adult myelodysplastic or myeloproliferative diseases. It may involve different organs including the orbit, skin, lymph nodes, bone, gastrointestinal tract, breast, central nervous system, and lung. Cardiac involvement with MS is an exceedingly rare finding. We report a very rare case of left ventricular cardiac chloroma accidentally discovered by transthoracic echocardiography (TTE) and confirmed by cardiac magnetic resonance (CMR) in an old aged male patient with acute myeloid leukemia (AML) French-American-British (FAB)-class M5. Unfortunately, shortly after a prompt start of AML palliative chemotherapy protocols, the patient died due to massive intracranial hemorrhage (ICH).
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Abdelnabi et al. (2019) conducted a case report in Cardiac chloroma / myeloid sarcoma in acute myeloid leukemia (n=1). Palliative chemotherapy was evaluated. A rare case of left ventricular cardiac chloroma was discovered by echocardiography and MRI in an elderly male with acute myeloid leukemia who subsequently died from intracranial hemorrhage.
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