Key result
A QLV ratio ≤0.70 in cardiac resynchronization therapy patients was associated with significantly higher all-cause mortality (HR 2.1; 95% CI 1.2-3.7; P=0.01) and heart failure hospitalization.
Why the study?
Does suboptimum electric position of the left ventricular lead (QLV ratio ≤0.70) increase mortality and heart failure hospitalization in patients receiving cardiac resynchronization therapy?
Cohort (n=329)
No
Does suboptimum electric position of the left ventricular lead (QLV ratio ≤0.70) increase mortality and heart failure hospitalization in patients receiving cardiac resynchronization therapy?
Effect estimate: HR 2.1 (95% CI 1.2-3.7)
p-value: p=0.01
Suboptimum electric position of the left ventricular lead (QLV ratio ≤0.70) during CRT implantation is a significant predictor of increased heart failure hospitalization and mortality.
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QLV ratio ≤0.70 may aid risk stratification in CRT; leaves open whether lead optimization improves outcomes.
Roubíček et al. (2015) conducted a cohort in Left bundle branch block or intraventricular conduction delay treated with cardiac resynchronization therapy (n=329). QLV ratio ≤0.70 vs. QLV ratio >0.70 was evaluated on All-cause mortality (HR 2.1, 95% CI 1.2-3.7, p=0.01). A QLV ratio ≤0.70 in cardiac resynchronization therapy patients was associated with significantly higher all-cause mortality (HR 2.1; 95% CI 1.2-3.7; P=0.01) and heart failure hospitalization.
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